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Cortisol, commonly called the "stress hormone," is a naturally-occurring steroid hormone that is released in response to stress. It is involved in a wide range of processes in the body, such as metabolism, inflammation, blood pressure regulation and bone formation, according to Johns Hopkins Medicine. Corticosteroids are synthetic forms of cortisol that work by decreasing inflammation and suppressing the immune system, according to Cleveland Clinic. Left untreated, excess inflammation can damage healthy tissue, as well as cause redness, swelling and pain.
Corticosteroids are important in the treatment of many inflammatory, allergic, immunologic, and malignant disorders
In the October 6, 2020 issue of the Journal of the American Medical Association, 3 recent studies were presented that all agreed that corticosteroids are beneficial in the treatment of patients with severe Covid-19 infection. Patients requiring the use of ventilators and/or oxygen appeared to derive the most benefit.
An accompanying editorial reviewed the benefits of corticosteroids not only in Covid-19 patients but also in patients with non-Covid-19 adult respiratory distress syndrome (ARDS), a common cause of respiratory failure in hospitalized adults. Because of the many Covid-19 trials initiated this year, much has been learned about the use of corticosteroids in these critically-ill patients that can generate more research and also hope for many seriously-ill patients.
Corticosteroids are inexpensive and useful in many conditions. These readily available drugs can immediately be utilized for those Covid-19 patients who need them. President Trump received the corticosteroid dexamethasone as part of his Covid-19 treatment regimen.
For more information:
https://jamanetwork.com/journals/jama/fullarticle/2770275?resultClick=1